The Stem Cell Ophthalmology Treatment Study II (SCOTS 2) is the largest study in the world using autologous (from the patient themselves) Bone Marrow Derived Stem Cells. We have published 5 articles in high quality, peer-reviewed medical and scientific journals and have 2 additional under review and several more planned in the next 2 years. We are interested in patients with vision loss as a consequence of optic nerve or retinal diseases. We have treated over 47 different eye diseases including major diseases such as glaucoma, NAION, optic atrophy, hereditary optic neuropathies, Age Related Macular Degeneration (AMD), Diabetic Retinopathies, Stargardts, Retinitis Pigmentosa, hereditary maculopathies and retinopathies. We are not substituting for standard of care- we wish patients to have completed all routine treatment that is available before consulting us.
The Neurologic Stem Cell Treatment study (NEST) is the largest neurologic study using autologous (from the same person) Bone Marrow Derived Stem Cells. We are interested in the numerous neurologic diseases and degenerations that are present. The major categories include Chronic Stroke (CVA), Parkinson's Disease, Multiple Sclerosis ( RR, PP, PR, SP), Traumatic Brain Injury (TBI), Peripheral Neuropathy (including Diabetic Neuropathy) but diseases are considered on a case by case basis. Typically patients receive BMSC intravenously and intranasally.
Spinal Cord Injury
The Stem Cell Spinal Cord Injury Exoskeleton & Virtual Reality study (SciExVR) is the most advanced and progressive spinal cord injury study using autologous Bone Marrow Stem Cells. We use a proprietary approach of injecting BMSC paraspinal (next to and just into the intervertebral foramen) at, above and below the area of injury - a total of 6 injections. This is followed by intravenous and intranasal BMSC. Depending on the patients situation and access to equipment, they may then be assigned to standard physical therapy , exoskeleton work or virtual reality supplementation. Our goal is recovery of sensory, autonomic and muscular function to the extent possible.
Autism Spectrum Disorder
The Alzheimer's, Autism, Cognitive Impairment Stem Cell Treatment study (ACIST) is an IRB approved, NIH registered (NCT 3724136) using autologous (from the patient themselves) Bone Marrow Derived Stem Cells in the treatment of Autism Spectrum Disorder (ASD) in patients over the age of 18. Evaluation with standard ASD testing including the AQ test is required for evaluation. There are a number of preclinical and clinical publications suggesting that BMSC may be of help in various neurologic diseases. One of the more recent university based studies, Autologous Umbilical Cord Blood Infusion for Children With Autism Spectrum Disorder (ASD) has been conducted at Duke University Medical Center in North Carolina. ACIST is not substituting for standard of care- we wish patients to have completed all routine treatment that is available before considering participation in ACIST.
Alzheimer's & Dementias
Alzheimer's Disease and other Dementias can be deeply painful to both patients and caregivers. The Alzheimer's, Autism, Cognitive Impairment Stem Cell Treatment study (ACIST) is an IRB approved, NIH registered clinical study listed on www.clinicaltrials.gov NCT 3724136. It is using Bone Marrow Derived Stem Cells (BMSC) in the treatment of these diseases. Patients are first evaluated with the Mini-Mental Status Exam and must score in what is considered the range for dementia before being admitted to the study. Eligible conditions may include Alzheimer's Disease (ALZ), Lewy Body Dementia, Multi-infarct Dementia, CADASIL Dementia and others. Patients are assigned to arms that may use BMSC intravenously, intravenously and intranasally or intravenously with Near Infrared Light (NIR) therapy. The scientific literature reports potential benefit of both approaches.
Resisting aging and the deterioration of our bodies has been a goal of mankind for recorded time. With the arrival of stem cell treatments and regenerative medicine, greater strides are being made today than at any point in history. Exploration of Proteomics- the study of the proteins produced by our cells and Metabolomics- the systematic identification and quantification of the small molecule metabolic products -is identifying factors that maintain youthful cells and those that promote aging. Bone Marrow Stem Cells (BMSC) which circulate in small numbers to respond to injury, may have an important role to play in resisting aging. Our goal is recovery of integumentary (skin) and muscular function to the extent possible.
For more information visit each of the studies individually.